This memo provides information for the Internet community. It does not specify an Internet standard of any kind. Distribution of this memo is unlimited.
このメモは、インターネット・コミュニティに情報を提供します。 このメモは、いかなる種類のインターネット標準を規定するものでもありません。 このメモの配布に制限はありません。
Copyright (C) The Internet Society (2004).
This document registers the MIME sub-type application/sbml+xml, a media type for SBML, the Systems Biology Markup Language. SBML is defined by The SBML Team at the California Institute of Technology and interested members of the systems biology community.
この文書は、 SBML — システム生物学マーク付け言語の MIME 亜型
application/sbml+xml
を登録します。
SBML は California Institute of Technology の SBML
組とシステム生物学コミュニティの関心ある参加者により定義されました。
SBML is an XML format for representing and exchanging models of biochemical reaction networks used in systems biology. SBML:
SBML はシステム生物学で使われる生化学反応網の模型の表現と交換のための XML の書式です。 SBML は、
- o enables researchers in systems biology to use multiple tools, such as simulators, editors, differential-equation solvers, and visualizers, on a single model without rewriting the model for each tool;
- o enables researchers and publishers to make models available on-line to other researchers even if they use a different software environment;
- o enables models, and the intellectual effort put into them, to survive beyond the lifetime of the software tools used to create them.
Currently, about 60 software applications use SBML, and researchers are using these applications to develop quantitative and qualitative computational models, mostly in cell biology. In addition, several consortia and alliances have standardized SBML as their model definition language. The SBML community hopes that a standardized MIME media type will help researchers share models on a larger scale, drawing more heavily on the capabilities of the world-wide web.
現在、60くらいのソフトウェア応用が SBML を使っており、 研究者はそれらの応用を、とりわけ細胞生物学で、 定量的で定性的な計算的模型の開発に使用しています。 加えて、いくつかの consortium や alliance が模型定義言語として SBML を標準としています。 SBML コミュニティは標準化された MIME 媒体型が研究者が模型をより大きな範囲で共有し、 世界規模ウェブの能力をより大きく引き出す助けとなると期待しています。
A detailed exposition of SBML and its uses within the systems biology community is available in references [HUCKA2003], [FINNEY2003], and [HUCKA2004].
SBML とシステム生物学コミュニティでの使用についての詳細な説明は参考文献 [HUCKA2003], [FINNEY2003], [HUCKA2004] にあります。
This section registers application/sbml+xml as a MIME media type according to the parameters set forth in [RFC2048].
この節は application/sbml+xml
を RFC 2048
に示された引数に従って MIME 媒体型として登録します。
- MIME media type name
- application
- MIME subtype name
- sbml+xml
- Required parameters
- none.
- Optional parameters
- none.
There is no charset parameter. Character handling has identical semantics to the case where the charset parameter of the "application/xml" media type is omitted, as described in section 3.2 of [RFC3023]. Note that SBML level 2 is defined to have UTF-8 encoding [SBML2-1, section 4.1].
charset
引数はありません。文字の取扱いは
application/xml
媒体型で charset
引数が省略された場合として RFC 3023 の3.2節に記述されているのと同じ意味を持ちます。
SBML 水準2は UTF-8 符号化を持つものと定義されていることに注意してください。
- Encoding considerations
- Same as described in section 3.2 of [RFC3023].
- Security considerations
The security considerations described in section 7 of [RFC3470] all potentially apply to sbml+xml documents. In particular, sbml+xml documents might contain the results of proprietary biological research that their owner may wish to keep private.
The XML schema for sbml+xml provides for no active or executable content.
RFC 3470 の7節に記述された安全上の考察がすべて潜在的に
sbml+xml
文書に適用されます。特に、
sbml+xml
文書は所有者が私的なままにしておきたいと思う独占的な生物学的研究結果を含んでいるかもしれません。
sbml+xml
の XML schema は動的・実行可能な内容を提供しません。
- Interoperability considerations
- The information in an sbml+xml document describes an abstract model of biochemical reactions. It is not tied to any particular software application, and indeed the primary purpose of SBML is to make these models readable and writable by many different software applications.
sbml+xml
文書の情報は生化学反応の抽象模型として記述されています。
特定のソフトウェア応用とは結び付けられておらず、 SBML
の主目的も模型を多くの異なるソフトウェア応用から読み書き可能にすることにあります。
This might seem to make sbml+xml more appropriate for the "Model" primary content type [RFC2077], but SBML models are not guaranteed to have the required three orthogonal dimensions. SBML models, rather, involve interacting entities that exist within compartments. However, ideally, browsers and other software that reads sbml+xml would give a human reader multiple choices of how to view the document: in a data-visualization tool, in a model editor, in a differential-equation analyzer, etc.
ということは sbml+xml
は Model
一次内容型の方が適切に思えるかもしれませんが、 SBML 模型は3つの直交次元を必要とするとは限りません。
SBML 模型は、そうではなく、区画の中に存在する相互作用する実体に関するものです。
しかし、理想的には、 sbml+xml
を読む閲覧器や他のソフトウェアは文書をどう表示するかについて人間の読者に複数の選択肢、
たとえばデータ可視化工具でみるか、
模型編集器で開くか、微分方程式解析器に与えるか、
というような選択肢を与えることとなるでしょう。
The systems biology community has and will continue to release new levels and versions of the SBML schema and semantics. New versions attempt to be backward compatible with old versions, but sometimes small incompatibilities are introduced. Every sbml+xml document contains its level and version; programs that read sbml+xml should read this information to be sure they correctly interpret the remainder of the document.
システム生物学コミュニティは新しい水準と版の SBML schema
や意味を出し続けてきましたし、これからもそうし続けることになるでしょう。
新しい版は古い版と後方互換であるようにしてはいますが、
時々小さな非互換性が持ち込まれることがあります。すべての sbml+xml
文書は水準と版を含んでいます。 sbml+xml
を読むプログラムはこの情報を読んで、文書の残りの部分を正しく解釈できることを確かめるべきです。
- Published specification
- A list of all current SBML specifications and related documents is maintained at:
すべての現行の SBML 仕様書と関連文書の一覧は
http://sbml.org/documents
で管理されています。
Current specifications are:
現行の仕様書は、次のものです。
SBML level 2, version 1 http://sbml.org/specifications/sbml-level-2-v1.ps http://sbml.org/specifications/sbml-level-2-v1.pdf > SBML level 1, version 2 http://sbml.org/specifications/sbml-level-1-v2.ps http://sbml.org/specifications/sbml-level-1-v2.pdf > SBML level 1, version 1 http://sbml.org/specifications/sbml-level-1-v1.ps http://sbml.org/specifications/sbml-level-1-v1.pdf
All specifications are authored by and available in hardcopy form from The SBML Team (see below for mailing information).
すべての仕様書は SBML 組 (後のメイル情報を参照) により執筆され、 紙版で提供されています。
- Applications which use this media type
- The following application and database projects read and/or write models in sbml+xml format. Currently, most do not encode or decode MIME-format messages. Hopefully the registration of sbml+xml will make it easier for these projects to connect through a broader infrastructure, such as the creation of repositories of models on the world-wide web.
次の応用とデータベース計画が sbml+xml
形式の模型を読んだり書いたりします。現在、ほとんどが
MIME 形式のメッセージを符号化したり復号したりしません。
sbml+xml
の登録によってこれらの計画がより広い基盤により接続する、
たとえば世界規模ウェブ上で模型の倉庫を作成することが容易になるであろうと望んでいます。
BALSA BASIS BioCharon biocyc2SBML BioGrid BioNetGen Bio Sketch Pad BioSpreadsheet BioUML BSTLab CADLIVE CellDesigner Cellerator Cellware COPASI Cytoscape DBsolve Dizzy E-CELL ecellJ ESS Gepasi Jarnac JDesigner JigCell JSIM JWS Karyote KEGG2SBML Kinsolver (planned) libSBML MathSBML MMT2 Modesto MOMA (planned) Monod NetBuilder PathArt PathScout PaVESy PathwayBuilder ProcessDB (planned) SBW SCIpath SigPath SigTran Simpathica SimWiz StochSim STOCKS Trelis Virtual Cell VLX Suite WinSCAMP
A list of SBML-enabled applications, along with URLs for more information about them, is maintained at http://sbml.org.
SBML に対応した応用の一覧とそれら応用についての更なる情報の URL は http://sbml.org で管理されています。
- Additional information
- For further information, contact:
更なる情報については、
Michael Hucka mhucka@caltech.edu > Andrew Finney afinney@cds.caltech.edu > The SBML Team http://sbml.org sbml-team@caltech.edu Control and Dynamical Systems, MC 107-81 California Institute of Technology Pasadena, CA 91125 USA
に連絡してください。
- Intended usage
- LIMITED USE
- Author/Change Controller
- The SBML specification is a free, open, community effort organized and edited by The SBML Team. The SBML Team has change control over the specification.
SBML 仕様書は自由で開かれたコミュニティ努力により組織化されたものであり、 SBML 組により編集されています。 SBML 組が仕様書の変更権を持ちます。
The SBML Team and interested members of the systems biology community meet regularly at the "Workshops on Software Platforms for Systems Biology". Information about past and planned workshops is maintained at:
SBML 組とシステム生物学の缶りんある参加者は 「システム生物学ソフトウェア環境研究会」で定期的に会合しています。 過去と計画中の研究会の情報は
http://sbml.org/workshops
で管理されています。
Security considerations for sbml+xml are discussed in the "Security Considerations" heading in the IANA registration in section 2.
sbml+xml
の安全については 2章の IANA 登録の
「安全に関して」の見出しで議論しています。
The following people contributed to the content of this document: Michael Hucka (Caltech), Andrew Finney (University of Hertfordshire).
次の人々がこの文書の内容に貢献してくださいました。 Michael Hucka (Caltech), Andrew Finney (University of Hertfordshire)。
[SBML2-1] Finney, A. and Hucka, M., "Systems Biology Markup Language (SBML) Level 2: Structures and Facilities for Model Definitions", June 28, 2003. Available from The SBML Team at: http://sbml.org/specifications/sbml- level-2-v1.pdf
[SBML1-2] Hucka, M., Finney, A., Sauro, H. and Bolouri, H., "Systems Biology Markup Language (SBML) Level 1: Structures and Facilities for Basic Model Definitions", August 28, 2003. Available from The SBML Team at: http://sbml.org/specifications/sbml-level-1-v2.pdf
[FINNEY2003] Finney, A. and Hucka, M., "Systems Biology Markup Language: Level 2 and Beyond", Biochemical Society Transactions 31:1472-1473, December, 2003.
[HUCKA2003] Hucka, M., Finney, A., Sauro, H.M., Bolouri, H., Doyle, J.C., Kitano, H., Arkin, A.P., Bornstein, B.J., Bray, D., Cornish-Bowden, A., Cuellar, A.A., Dronov, S., Gilles, E.D., Ginkel, M., Gor, V., Goryanin, I.I., Hedley, W.J., Hodgman, T.C., Hofmeyr, J.-H., Hunter, P.J., Juty, N.S., Kasberger, J.L., Kremling, A., Kummer, U., Le Novere, N., Loew, L.M., Lucio, D., Mendes, P., Minch, E., Mjolsness, E.D., Nakayama, Y., Nelson, M.R., Nielsen, P.F., Sakurada, T., Schaff, J.C., Shapiro, B.E., Shimizu, T.S., Spence, H.D., Stelling, J., Takahashi, K., Tomita, M., Wagner, J., Wang, J., "The Systems Biology Markup Language (SBML): a Medium for Representation and Exchange of Biochemical Network Models", Bioinformatics 19(4):524-531, 2003.
[HUCKA2004] Hucka, M., Finney, A., Bornstein, B. J., Keating, S. M., Shapiro, B. E., Matthews, M., Kovitz, B. L., Schilstra, M. J., Funahashi, A., Doyle, J. C., and Kitano, H., "Evolving a Lingua Franca and Associated Software Infrastructure for Computational Systems Biology: The Systems Biology Markup Language (SBML) Project", Systems Biology, Vol. 1, 2004.
[RFC2048] Freed, N., Klensin, J. and J. Postel, "Multipurpose Internet Mail Extensions (MIME) Part Four: Registration Procedures", BCP 13, RFC 2048, November 1996.
[RFC2077] Nelson, S. and C. Parks, "The Model Primary Content Type for Multipurpose Internet Mail Extensions", RFC 2077, January 1997.
[RFC3023] Murata, M., St. Laurent, S. and D. Kohn, "XML Media Types", RFC 3023, January 2001.
[RFC3470] Hollenbeck, S., Rose, M. and L. Masinter, "Guidelines for the Use of Extensible Markup Language (XML) within IETF Protocols", BCP 70, RFC 3470, January 2003.
訳注: Charset のところで参照している RFC 3023 くらい Normative にしてもばちはあたらないと思いますが...
Ben Kovitz Control and Dynamical Systems, MC 107-81 California Institute of Technology Pasadena, CA 91125 USA
Phone: +1 626 395-6911 EMail: bkovitz@caltech.edu
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[1] 訳者より: システム生物学に詳しい方の review があると嬉しいです。